Imeglimin: Therapeutic Option for Achieving Glycemic Control

Dr. Subhash Kumar

Imeglimin is a new class of drug which has introduced recently. The molecular mechanisms are unknown, although imeglimin improves insulin sensitivity in humans. Pre-clinical stu..और देखें»

Identification of Mutations, Expression Alterations and Fusion Transcripts by Next Generation RNAseq in Castration-Resistant Prostate Cancer Cell lines with Possible Clinical Relevance

Yuanjun Ma, Yali Miao, Zhuochun Peng, Johanna Sandgren, Teresita Díaz De Ståhl, Lena Lennartsson, Sten Nilsson and Chunde Li

Androgen Deprivation Therapy (ADT) would benefit prostate cancer patients initially but cancer cells can eventually develop castration resistance. In this study, we compared and..और देखें»

The Rhesus Monkey: A Nonhuman Primate Model For T2DM- Associated Gene Screening

Barbara C. Hansen, Rania Shamekh, Ola Hansson, Peter Almgren, Temuri Budagov, Ellen Linden, Jeffrey Pessin and Gil Atzmon

To examine the genetic basis of the spontaneous development of Type 2 diabetes mellitus (T2DM), we have conducted an initial genome wide association study (GWAS) using Affymetri..और देखें»

Pioglitazone Increases Serum DPP-4 Level in Type 2 Diabetes Mellitus

Ippei Kanazawa, Sayuri Tanaka, Masakazu Notsu and Toshitsugu Sugimoto

Objective: The aim of this study is to clarify the effect of pioglitazone on serum Dipeptidyl peptidase-4 (DPP-4) level in type 2 diabetes mellitus.

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An update on Etiopathogenesis of Diabetic Kidney Disease and their Therapeutic Implications- A Systematic Review

Kulvinder Kochar Kaur *, Gautam Nand K Allahbadia, Mandeep Singh

As we all know Diabetic Kidney Disease (DKD) represents the commonest etiology for Chronic Kidney Disease (CKD) along with end-stage renal Disease (ESRD). Earlier we have review..और देखें»

Dysglycemia and Dyslipidemia Models in Nonhuman Primates: Part III. Type I or II Diabetogenic Effects of Streptozocin

Yongqiang Liu, Jiajun Gao, Xiaoli Wang, Yixin Jim Wang and Yong-Fu Xiao

Streptozocin (STZ), a naturally occurring glucosamine-nitrosourea compound, has been used for diabetogenic induction in animals for diabetic research due to its high toxicity to..और देखें»